How to Test and Avoid Multicollinearity in Mixed Linear Models in R?

Multicollinearity is a common issue in regression analysis, including mixed linear models, where predictor variables are highly correlated. This can lead to inflated standard errors, unreliable coefficient estimates, and difficulties in determining the individual effect of each predictor. This article will guide you through the process of testing and avoiding multicollinearity in mixed linear models using R.

Understanding Multicollinearity

Multicollinearity occurs when two or more predictor variables in a regression model are highly correlated, meaning that one predictor variable can be linearly predicted from the others with a substantial degree of accuracy. This can compromise the statistical significance of the predictors.

Identifying Multicollinearity

There are several methods to detect Multicollinearity in the R Programming Language So we will discuss all of them.

Method 1: Correlation Matrix

A correlation matrix helps identify pairs of highly correlated predictors.

R
# Load necessary library
library(corrr)

# Sample data (replace with actual data)
data <- data.frame(x1 = rnorm(100), x2 = rnorm(100), x3 = rnorm(100))
data$x2 <- data$x1 * 0.8 + rnorm(100) * 0.2  # Introduce correlation

# Correlation matrix
cor_matrix <- correlate(data)
print(cor_matrix)

Output:

# A tibble: 3 × 4
term x1 x2 x3
<chr> <dbl> <dbl> <dbl>
1 x1 NA 0.966 0.0707
2 x2 0.966 NA 0.0719
3 x3 0.0707 0.0719 NA

Method 2: Variance Inflation Factor (VIF)

VIF quantifies how much the variance of a regression coefficient is inflated due to multicollinearity. VIF values above 10 indicate high multicollinearity.

R
# Load necessary libraries
install.packages("car")
library(car)

# Fit a linear model to check VIF
model <- lm(x1 ~ x2 + x3, data = data)
vif_values <- vif(model)
print(vif_values)

Output:

      x2       x3 
1.005201 1.005201

Testing Multicollinearity in Mixed Linear Models

Now we will discuss methods for Testing Multicollinearity in Mixed Linear Models.

1. Fit the Mixed Linear Model

Mixed linear models account for both fixed and random effects. Use the lme4 package for fitting mixed models.

R
# Load necessary library
install.packages("lme4")
library(lme4)

# Sample data (replace with actual data)
data <- data.frame(group = rep(1:20, each = 5), y = rnorm(100), x1 = rnorm(100),
                   x2 = rnorm(100))
data$x2 <- data$x1 * 0.8 + rnorm(100) * 0.2  # Introduce correlation

# Fit a mixed linear model
mixed_model <- lmer(y ~ x1 + x2 + (1 | group), data = data)
summary(mixed_model)

Output:

Linear mixed model fit by REML ['lmerMod']
Formula: y ~ x1 + x2 + (1 | group)
Data: data

REML criterion at convergence: 296.6

Scaled residuals:
Min 1Q Median 3Q Max
-1.86930 -0.76025 -0.02742 0.67221 2.27513

Random effects:
Groups Name Variance Std.Dev.
group (Intercept) 0.000 0.000
Residual 1.116 1.056
Number of obs: 100, groups: group, 20

Fixed effects:
Estimate Std. Error t value
(Intercept) 0.145171 0.105931 1.370
x1 0.103170 0.438155 0.235
x2 0.007077 0.540438 0.013

Correlation of Fixed Effects:
(Intr) x1
x1 -0.076
x2 0.074 -0.975
optimizer (nloptwrap) convergence code: 0 (OK)
boundary (singular) fit: see help('isSingular')

2. Checking VIF in Mixed Models

While lme4 does not directly provide VIF for mixed models, we can use the car package to compute VIF for the fixed effects.

R
# Extract fixed effects data
fixed_effects_data <- model.matrix(~ x1 + x2, data = data)
vif_values_mixed <- vif(lm(y ~ x1 + x2, data = as.data.frame(fixed_effects_data)))
print(vif_values_mixed)

Output:

      x1       x2 
19.91257 19.91257

Avoiding Multicollinearity in Mixed Linear Models in R

Now we will discuss how to we remove and Avoiding Multicollinearity in Mixed Linear Models in R Programming Language.

1. Remove Highly Correlated Predictors

If two predictors are highly correlated, consider removing one of them.

R
# Removing highly correlated predictor
data_reduced <- data[ , !(names(data) %in% "x2")]
data_reduced 

Output:

    group            y          x1
1 1 0.562267345 -0.14126176
2 1 -0.097412499 -1.00537758
3 1 1.016455218 0.15615571
4 1 -1.156167394 0.23363361
5 1 2.320860224 0.35558761

The code provided removes a highly correlated predictor variable (x2) from the dataset data, resulting in a new dataset data_reduced that excludes this variable. This step is typically taken to address issues of multicollinearity in regression analysis, enhancing the reliability and stability of the model’s estimates. After this operation, the data_reduced dataset contains all the original rows but only the columns that were not excluded, thereby retaining the necessary predictors for subsequent analysis.

2. Combine Correlated Predictors

Combining correlated predictors into a single predictor through methods like principal component analysis (PCA).

R
# Load necessary library
install.packages("psych")
library(psych)

# Principal Component Analysis
pca_result <- principal(data[ , c("x1", "x2")], nfactors = 1, rotate = "none")
data$pca <- pca_result$scores
data$pca 

Output:

                PC1
[1,] -0.143816711
[2,] -1.046311124
[3,] 0.205614301
[4,] 0.229269889
[5,] 0.482887033

3. Regularization Techniques

Using regularization methods like Ridge regression (L2 penalty) or Lasso regression (L1 penalty) to handle multicollinearity.

R
# Load necessary library
install.packages("glmnet")
library(glmnet)

# Prepare data for glmnet
x <- model.matrix(y ~ x1 + x2, data = data)
y <- data$y

# Fit a Ridge regression model
ridge_model <- cv.glmnet(x, y, alpha = 0)
plot(ridge_model)

# Fit a Lasso regression model
lasso_model <- cv.glmnet(x, y, alpha = 1)
plot(lasso_model)

Output:

Avoid Multicollinearity in Mixed Linear Models in R

Conclusion

Addressing multicollinearity in mixed linear models is crucial for reliable and interpretable results. By using correlation matrices, VIF, PCA, and regularization techniques, you can effectively test and mitigate the impact of multicollinearity in your models. R provides robust tools and packages to facilitate these analyses, ensuring that your mixed linear models are both accurate and insightful.