Amide Vs. Amine

The difference between Amides and Amines are as follows:

Features

Amides

Amines

Functional Group

Amides have a carbonyl group (C=O) bonded to an amine group (NH2)

Amines have a nitrogen atom bonded with one or more alkyl group.

Nomenclature

Amides are named using the carboxylic acid nomenclature.

Amines are named based on the number of carbon atoms bonded to the nitrogen atom.

Basicity

Amides are weak bases due to the carbonyl group.

Amines are basic because the nitrogen atom has a lone pair of electrons.

Reactions

Amides can undergo hydrolysis with an aqueous acid or base. This breaks the amide bond to produce a carboxylic acid and either ammonia or an amine.

Amines can undergo various reactions. These include nucleophilic substitution, electrophilic substitution, and redox reactions.

Boiling Point

Amides have relatively higher boiling point.

Amines have relatively lower boiling point.

Amides

Amide is an organic compound. It is also known as an organic amide or carboxamide. It contains a carbonyl functional group that is bonded with a nitrogen atom. The simplest amide is a derivative of ammonia NH3, here one hydrogen atom is replaced by an acyl group.

In this article, we will define Amide, its types, structures, along with its properties.

Amide Functional Group

Nomenclature

Amides are named by replacing the -oic acid or -ic acid ending of the parent carboxylic acid with -amide. For example, ethanoic acid becomes ethanamide

Nature

Neutral or very weak acids

Appearance

White crystalline solid

Odor

Ethanamide, a simple amide, is said to smell like mice.

Density

Generally, they are denser than water.

Melting Point

Amides have high melting points.

  • Melting point of butyramide is 115°C
  • Melting point of benzamide is 132°C

Boiling Point

Amides have high boiling points due to the presence of strong hydrogen bonds.

  • Boiling point of butyramide is 216°C
  • Boiling point of benzamide is 290°C

Solubility

Soluble in Water

Table of Content

  • What is Amide?
  • Amide Structure
  • Classifications of Amides
  • Amide Bond
  • Synthesis of Amide
  • Amide Vs. Amine

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