Animal Chimera
An animal chimera is a single organism composed of cells from two or more genetically distinct individuals. Chimeras can occur naturally through the fusion of embryos or be created artificially through techniques like cell transplantation or genetic engineering.
- Chimeras exhibit a mosaic of traits, with different cell populations retaining their own genetic characteristics.
- At least four parent cells are involved in the formation of chimeras, often through the fusion of two fertilized eggs or early embryos.
- Animal chimeras are used in biomedical research to study development, disease mechanisms, and potential therapies.
- There are ethical and regulatory considerations surrounding the creation and use of animal chimeras, particularly regarding their welfare and potential implications for human health.
- Common examples include mice with humanized immune systems for disease research and pigs with human organs for transplantation.
Also Read: Genetic Linkage
Chimera – Genetics
Chimera genetics refers to an organism containing cells with different genetic compositions. In genetics, human chimeras are individuals with cells from two or more genetically distinct sources. Identification of chimerism in humans involves genetic testing of multiple tissues or cells to detect variations in DNA profiles.
Chimerism can occur naturally through processes like twinning or fusion of embryos, and artificially through procedures like organ transplantation or gene therapy. Chimerism has applications in various fields like forensics, transplantation, and reproductive medicine. In this article, we will study the meaning of chimera, its formation, chimera in humans and its identification in detail.
Table of Content
- What is Chimera – Genetics?
- What Causes Chimerism?
- Symbiotic Chimerism in Anglerfish
- Animal Chimera
- Human Chimera
- Germline Chimera in Genetic Engineering
- Chimera Diagnosis
- Advantages of Chimera
- Disadvantages of Chimerism