Autosomal Dominant Pedigree Pattern
- If one of the parents has the autosomal dominant gene then there is a 50% chance that children are affected by the disease.
- If both the parent are hemizygous for the disease then the child is unaffected (get recessive traits from both the parent)
- Progeny has affected genes then the genes pass on to the next generation.
- In pedigree, if the children are affected then their parents are also affected (at least one parent)
- There is a possibility that only one sibling is affected by the disease and not the other sibling.
Autosomal Dominant Inheritance
The transfer of genetic traits from parents to children either through sexual or asexual reproduction is referred to as inheritance. All the genetic material for the offspring comes from the parents. Children inherit genes from their parents (characteristics), which is why they resemble their parents. Typically, parents pass on their blood type, eye color, hair color, facial shape, and eye color to their children. This also includes parents’ diseases being passed on to their children.