Clinical Significance of RTK
Tyrosine kinases are particularly significant today due to their potential use in cancer therapy. Imatinib is a medication that inhibits the activity of certain tyrosine kinases by binding to their catalytic cleft. During infection, a variety of viruses target tyrosine kinase function. Furthermore, tyrosine kinase can sometimes act improperly, leading to non-small cell lung cancer. Non-small cell lung cancer is a frequent and widespread cancer that kills more people than breast, colorectal, and prostate cancer combined.
Receptor Tyrosine Kinase Signaling
Cell signalling is a cell’s capacity to accept, process, and transmit messages to its surroundings and to itself. Cell signalling is a basic characteristic of all prokaryotic and eukaryotic cellular life. Extracellular signals (or signals that originate outside of a cell) can be physical agents such as mechanical pressure, electricity, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas).