Differences Between Turner Syndrome and Klinefelter Syndrome
Feature |
Turner Syndrome |
Klinefelter Syndrome |
Chromosomal Abnormality |
Monosomy of counseling X chromosome (45 chromosomes with 44+XO) |
Trisomy of the X chromosome (47 chromosomes with 44+XXY) |
Gender Affected |
Females |
Males |
Incidence |
1 out of 2000 females is affected |
1 out of 1000 males is affected |
Physical Characteristics |
Short stature, underdeveloped breasts, lack of secondary sexual characteristics |
Masculine development with some feminine characteristics such as gynecomastia (development of breasts) |
Treatment |
Hormonal replacement therapy, Fertility treatment, and Psychological counseling |
Testosterone replacement therapy, Removal of excess breast tissue, Fertility treatment, and Psychological counseling |
Gonads |
Gonads are absent or nonfunctional. |
Gonads are present but atrophied. |
Risks |
Prone to diseases such as osteoporosis, cardiovascular problems, diabetes, and thyroid disorders. |
Prone to diseases such as osteoporosis, autoimmune disorders, breast cancer, and testicular cancer. |
Difference Between Turner Syndrome and Klinefelter Syndrome
Difference Between Turner Syndrome and Klinefelter Syndrome: Turner Syndrome and ​Klinefelter Syndrome​ are chromosomal disorders, caused by variations in the number of sex chromosomes. The main difference between Turner syndrome and Klinefelter syndrome is that Turner syndrome is a monosomy (one X chromosome is missing) while Klinefelter syndrome is a trisomy (one extra X chromosome is present).