Examples of Hoffmann Bromamide Reaction
Some examples of Hoffmann Bromamide Reaction
Preparation of Aniline
The preparation of Aniline from the Hoffmann Bromamide reaction is shown below,
CH3CONHPh + 3Br2 + 6NaOH → C6H5NH2 + CH3COONa + 3NaBr + 3H2O
Preparation of Methylamine
The preparation of Methylamine from the Hoffmann Bromamide reaction is shown below,
CH3CONH2 + 3Br2 + 6NaOH → CH3NH2 + CH3COONa + 3NaBr + 3H2O
Hoffmann Bromamide Reaction
Hoffmann Bromamide Reaction is named after the famous chemist August Wilhelm Von Hoffmann. If an amide is treated with Bromine in an aqueous or ethanolic solution of sodium hydroxide, the formation of amine takes place. It is used to synthesize primary aromatic and aliphatic amines.
In this article, we will explore the Hoffmann Bromamide Reaction, its mechanism, its applications, examples, and limitations in detail.
Table of Content
- What is Hoffmann Bromamide Reaction?
- Hoffmann Bromamide Reaction Mechanism
- Examples of Hoffmann Bromamide Reaction
- Hoffmann Bromamide Reaction Applications
- Limitations of Hoffmann Bromamide Reaction