Purification of Organic Compound

Question 1: What is the basic principle of chromatography?

Answer:

Chromatography is based on the idea of separating molecules in a mixture that has been added to the ground or solid and liquid stationary states (stable phase) while travelling with the help of a mobile phase. 

Question 2: What is the Rf value in chromatography?

Answer:

In paper chromatography, RF refers to the distance a fluid component goes up a chromatography plate. All chemicals have a common RF value for each solvent, and RF values are used to match unknown samples with known compounds.

Question 3: What are the four major purifying methods?

Answer:

Four major purifying methods are as follows:

  • Filtering
  • Crystalline Formation
  • Sublimation
  • Distillation

Question 4: How can sublimation be used to purify organic compounds?

Answer: 

Sublimation is the process of transforming a solid into a gas without passing through the liquid state. This technique can be used to purify compounds that are sublimable or have vapor pressures that reach atmospheric pressure well before they reach their melting temperatures.



Purification of Organic Compounds

Organic chemistry is the study of carbon-containing molecules’ structure, characteristics, content, reactions, and production. The majority of organic compounds contain carbon and hydrogen, but they may also contain a variety of other elements (e.g., nitrogen, oxygen, halogens, phosphorus, silicon, and sulfur).

Organic chemistry was originally limited to the study of molecules created by living organisms, but it has now expanded to encompass man-made substances.

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Methods of Purification of Organic compounds

Various methods used for the purification of complex organic compounds are discussed below in this article....

Sublimation

Conversion of a substance from the solid state to the gaseous state without its becoming liquid. An example is a vaporization of frozen carbon dioxide (dry ice) at ordinary atmospheric pressure and temperature....

Crystallization

Crystallization is a method used for the purification of substances. The separation technique separates solids from a liquid....

Distillation

Distillation is the process of selectively boiling a component in a liquid mixture and then condensing it thereafter. It is a method of separation that can be applied to either get more of one particular component out of a mixture or to separate it out almost completely....

Differential Extraction

Differential extraction is the method of extracting an organic component from its aqueous solution by shaking it with an organic solvent in which it is insoluble.As an example, consider the separation of an oil-water mixture....

Chromatography

Chromatography is a technique used to separate mixtures. The mixture is passed through another substance, in this case, filter paper. The different colour ink particles travel at different speeds through the filter paper allowing us to see the constituent colours of the pen ink....

Types of Chromatography

Chromatography is of two types:...

FAQs on Purification of Organic Compound

Question 1: What is the basic principle of chromatography?...