Stereochemistry of SN2 Reactions

The seterocenter of the subtrate is attacked by the nucleophile in two ways that are,

  • Frontside Attack
  • Backside Attack

Frontside Attack: In frontside attack the nuclephile attacks from the same side where the leaving group is present, in this case the stereochemical configuration of the product is retained.

Backside Attack: In backside attack the nuclephile attacks from the opposite side of the carbon-leaving group bound, in this case the stereochemical configuration of the product is inversed.

SN2 Reaction Mechanism

SN2 also called Substitution Nucleophilic Bimolecular reaction mechanism is an essential process in organic chemistry. It involves a nucleophile attacking the central atom while a leaving group is simultaneously displaced. The “SN” in SN2 stands for “substitution nucleophilic,” and the “2” indicates that the rate-determining step is bimolecular.

In this article, we will look into the SN2 reaction mechanism, its examples, energy diagrams, applications, etc.

Table of Content

  • What are SN2 Reactions?
  • SN2 Reaction Mechanism
  • Energy Diagram of SN2 Reaction Mechanism
  • Factors Affecting SN2 Reaction Mechanism
  • Properties of SN2 Reaction Mechanism
  • Stereochemistry of SN2 Reactions
  • Difference Between SN1 and SN2 Reaction Mechanism

Similar Reads

What are SN2 Reactions?

In an SN2 reaction, a strong nucleophile attacks the carbon atom to which the leaving group is attached, forming a new bond to the carbon via a backside attack. In contrast, the leaving group detaches from the reaction center in a concerted fashion. This reaction is characterized by its bimolecular nature, as both the nucleophile and the substrate are involved in the rate-determining step....

SN2 Reaction Mechanism

SN2 reaction mechanism proceeds through a concerted backside attack of a nucleophile upon an alkyl halide. The critical steps of the SN2 reaction mechanism can be summarized as follows:...

Energy Diagram of SN2 Reaction Mechanism

Energy diagram of an SN2 reaction mechanism shows a single curve since it is a single-step reaction. The products, CH3OH and Br–, are in a lower energy state compared to the reactants, CH3Br and OH–. The top of the curve represents the transition state, the highest-energy structure involved in the reaction....

Factors Affecting SN2 Reaction Mechanism

Factors affecting SN2 reactions are as follows:...

Properties of SN2 Reaction Mechanism

Pproperties of SN2 reaction mechanism are:...

Stereochemistry of SN2 Reactions

The seterocenter of the subtrate is attacked by the nucleophile in two ways that are,...

Difference Between SN1 and SN2 Reaction Mechanism

The difference between SN1 and SN2 reaction Mechanism are added in the table below,...

FAQs on SN2 Reaction Mechanism

What is SN2 Reaction Mechanism?...