What is Monohybrid Cross?

Monohybrid cross refers to the genetic inheritance that involves a single characteristic or trait like plant height, pod shape, etc. Mendel crosses two homozygous traits and forms a heterozygous trait which is known as a monohybrid cross or the inheritance of a single gene. Each gene has two versions that control a character that is called an allele. Through Punnett square, it can be easily shown.

After the monohybrid cross the heterozygous progeny is obtained which is called Fillial1 (F1) generation. And again cross is done between F1 progeny or heterozygous trait and the resulting progeny is called Fillial2 (F2) generation. Three of the resulting alleles exhibit the dominant trait, while one show the recessive trait, giving rise to a phenotypic ratio of 3:1. The ratio of the dominant allele, a heterozygous and recessive allele is 1:2:1 which is called as genotypic ratio.

Also Read: Laws of Inheritance

Monohybrid Cross – Inheritance of One Gene

Monohybrid cross occurs when two organisms with contrasting variations at a particular genetic locus are crossed. The traits being studied are influenced by multiple variations at a single gene location. The resulting offspring, known as the F1 generation, will all be heterozygous and express the dominant trait, masking the recessive trait. The monohybrid cross demonstrates Mendel’s law of dominance.

Table of Content

  • Monohybrid Definition
  • What is Monohybrid Cross?
  • How to carry out a Monohybrid cross?
  • Example of Monohybrid Cross
  • Huntington’s Disease
  • FAQs on Monohybrid Cross

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Monohybrid Definition

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What is Monohybrid Cross?

A monohybrid cross involves the inheritance of a single gene or trait by crossing individual with differing alleles for that gene, demonstrating Mendel’s Law of Dominance....

How to carry out a Monohybrid cross?

Monohybrid cross refers to the genetic inheritance that involves a single characteristic or trait like plant height, pod shape, etc. Mendel crosses two homozygous traits and forms a heterozygous trait which is known as a monohybrid cross or the inheritance of a single gene. Each gene has two versions that control a character that is called an allele. Through Punnett square, it can be easily shown....

Example of Monohybrid Cross

The monohybrid cross is carried out by carrying out following steps:...

Huntington’s Disease

Example of a monohybrid cross using pea plants with purple (P) and white (p) flower color as the trait is as follows;...

FAQs on Monohybrid Cross

Huntington’s is a genetic disorder that affect the brain and nervous system. That means the person having a dominant gene of this will be affected by Huntington’s disease. Symptoms include involuntary movements, mood swings, and cognitive decline. It is an autosomal dominant disorder, meaning a child of an affected parent has a 50% chance of inheriting the gene mutation. There is currently no cure for Huntington’s disease....