Enantiomers vs Stereoisomers

Difference Between Enantiomers and Diastereomers

Following are the differences between enantiomers and stereoisomers based on characteristics

Characteristic	Enantiomers	Stereoisomers
Definition	Mirror-image isomers with non-superimposable structures.	Molecules with the same molecular formula and connectivity but different spatial arrangements.
Chirality	Enantiomers are a specific type of stereoisomer that are chiral.	Stereoisomers include enantiomers and diastereomers.
Relationship	Enantiomers are a subtype of stereoisomers.	Stereoisomers encompass various types, including enantiomers.
Mirror Image	Enantiomers are mirror images of each other.	Stereoisomers may or may not be mirror images.
Superimposability	Enantiomers are non-superimposable.	Stereoisomers may or may not be superimposable.
Optical Activity	Enantiomers rotate plane-polarized light equally but in opposite directions.	Stereoisomers may exhibit different or similar optical activities.
CIP Configuration	Described using R and S configurations in the Cahn-Ingold-Prelog system.	Configuration may involve E/Z (geometric) or cis/trans (structural) descriptors.
Examples	L and D forms of amino acids are classic examples.	Geometric isomers like cis and trans forms in alkenes.

Enantiomers

Enantiomers are pairs of molecules with identical chemical composition but non-superimposable mirror images. They exhibit different optical activities and interact uniquely with polarized light. Their distinctive spatial arrangements around chiral centers result in unique properties, notably in their interaction with light.

In this article, we will learn about the definition of an enantiomer, its properties, various examples of enantiomers, and the difference between enantiomers, chirality, stereoisomers, and diastereomers.

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