Difference Between MHC Class 1 and MHC Class 2 Proteins
What is the Role of MHC Proteins in the Immune System?
The MHC proteins play a vital role in the immune system by presenting antigens to the immune cells, which triggers an immune response against foreign substances.
Can MHC Class I and MHC Class II Proteins Present the Same Antigen?
No, MHC Class I and MHC Class II proteins present antigens derived from different sources and interact with different types of T cells.
Are MHC Class I and MHC Class II Genes Polymorphic?
Yes, MHC genes are highly polymorphic, meaning they exist in different variants or alleles within a population, contributing to the diversity of antigen presentation.
What Happens if There is a Mismatch Between MHC Proteins During Organ Transplantation?
The Mismatched MHC proteins can lead to the immune response, as the recipient’s immune system may recognize the transplanted organ as foreign and mount an immune attack, resulting in organ rejection.
What is the function of MHC Class 2?
MHC Class II proteins aid in presenting antigens derived from extracellular pathogens to CD4+ T cells, facilitating immune responses
What is the structure of MHC-I?
MHC-I has an α chain associated with β2-microglobulin, forming a heterodimeric structure crucial for antigen presentation to CD8+ T cells.
Difference Between MHC Class 1 and MHC Class 2 Proteins
Difference Between Mhc Class 1 and Mhc Class 2 Proteins: The MHC (Major Histocompatibility Complex) proteins play a crucial role in the immune system by presenting antigens to the immune cells. Both MHC I and MHC II are responsible for distinguishing between self and non-self molecules, allowing the immune system to recognize and eliminate foreign invaders.
MHC Class I proteins are found on the surface of almost all nucleated cells in the body. MHC Class II proteins are primarily expressed on antigen-presenting cells, including dendritic cells, macrophages, and B cells. In this article, we will read about Major Histocompatibility Complex (MHC) proteins and the difference between MHC Class 1 and MHC Class 2 proteins.
Table of Content
- MHC Class I Proteins
- MHC Class II Proteins
- Difference Between MHC Class I and MHC Class II Proteins
- MHC I vs MHC II Diagram
- Conclusion – Difference Between MHC Class 1 and MHC Class 2 Proteins
- FAQs on Difference Between MHC Class 1 and MHC Class 2 Proteins