Structure of Adrenocorticotropic Hormone (ACTH)
Adrenocorticotropic hormone (ACTH) comprises 39 amino acids, with the initial 13, starting from the N-terminus, capable of forming α-melanocyte-stimulating hormone (α-MSH). This shared structure contributes to the darkened skin often observed in Addison’s disease. Subsequently, ACTH undergoes cleavage, yielding α-melanocyte-stimulating hormone (α-MSH) and CLIP, a peptide whose function in humans remains unclear. In the human body, ACTH has a total molecular weight of 4,540 atomic mass units (Da).
Adrenocorticotropic Hormone
Adrenocorticotropic hormone (ACTH), also known as adrenocorticotropin or corticotropin, is a peptide hormone synthesised and released by the anterior pituitary gland. It serves both as a therapeutic agent and a diagnostic tool. ACTH plays a crucial role in the functioning of the hypothalamic-pituitary-adrenal axis and is typically generated in reaction to physiological stress. This article will cover Adrenocorticotropic hormone (ACTH) functions and structure in detail.
Table of Content
- What is Adrenocorticotropic hormone?
- Structure of Adrenocorticotropic hormone
- ACTH Test
- ACTH Normal Range
- Low level ACTH
- High level ACTH
- Disorders of ACTH hormone
- Functions of Adrenocorticotropic hormone
- Mechanism
- Conclusion
- FAQ on Adrenocorticotropic hormone