What is meant by missense mutation?
Missense mutation is defined as a type of mutation where substitution of different amino acid takes place into the amino acid sequence that results into nucleotide change. Missense mutation is also known as non-synonymous substitution. Stop codon is not generated in missense mutation for terminating the sequence of amino acid synthesis. In missense mutation if new amino acid consists of similar features as in the original amino acid, the missense mutation is called as conservative mutation. If new amino acid has different properties as compared to the original one, then this type of missense mutation is known as non-conservative mutation. The mutated protiens can become non functional or else can have different functions compared to original protein.
Difference Between Missense and Nonsense Mutation
Missense and Nonsense mutations are the two different types of point mutations also known as single nucleotide substitutions that introduce changes in the ultimate protein product. DNA in the body changes because of various internal and environmental factors. Due to this two types of changes that occur in DNA are DNA damage and DNA mutations. The below article covers the two such mutations that occur in DNA.
Table of Content
- Difference between Missense and Nonsense Mutation
- What is meant by missense mutation?
- What is meant by nonsense mutation?
- FAQs on Missense and Nonsense Mutation