Examples of Nitration

Various example of Nitration with reactions are,

Nitration of Aniline

The nitration of Aniline is shown in the reaction below,

C6H5NH2 (conc. HNO3 + conc. H2SO4) → C6H4NH2NO2(Meta Product)(Major Product) + C6H4NH2NO2(Ortho-Para Product)(Minor Product)

Methyl Benzoate Nitration

The nitration of Methyl Benzoate is shown in the reaction below,

C6H5COOCH3 (conc. HNO3 + conc. H2SO4) → C6H5COOCH3(Ortho/Para Product)(Major Product)

Nitration of Chlorobenzene

The nitration of Chlorobenzene is shown in the reaction below,

C6H5Cl (conc. HNO3) → C6H4ClNO2(Ortho Product) + C6H4ClNO2(Para Product)(Minor Product)

Nitration of Toluene

The nitration of Toluene is shown in the reaction below,

C6H5CH3 (conc. HNO3 + conc. H2SO4) → C6H2CH3(NO2)3

Nitration of Benzoic Acid

The nitration of Benzoic Acid is shown in the reaction below,

C6H5COOH (conc. HNO3 + conc. H2SO4) → C6H4COOHNO2(Ortho/Para Product)

Nitration

Nitration is a chemical process that helps introduce nitro group (-NO2) in an organic compound. But sometimes, the term is misunderstood to represent different processes, like forming nitrate esters among nitric acids and alcohols, which takes place in synthesizing nitroglycerin. The main difference between nitrates and nitro compounds is the bonding of nitrogen atoms with oxygen or carbon.

In this article, we will learn about, Nitration Definition, Nitration Mechanism, Types of Nitration, Nitrating Agent, and others in detail.

Table of Content

  • What is Nitration?
  • Nitration Mechanism
  • Types of Nitration
  • Electrophilic Substitution Mechanism
  • Nitrating Agents
  • Examples of Nitration
  • Factors Affecting Nitration
  • Applications of Nitration

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What is Nitration?

Nitration is a chemical process in organic chemistry that involves introducing a nitro group (─NO2) into an organic compound, typically onto an aromatic ring. This process is often carried out using a mixture of concentrated nitric acid(HNO3) and sulfuric acid(H2SO4), which produces the active species known as the nitronium ion (NO2+)....

Nitration Mechanism

The mechanism for the Nitration reaction can be broken down into the following steps:...

Types of Nitration

Following are the different types of Nitration that are,...

Aromatic Nitration

Aromatic nitration is a chemical process used to synthesize various compounds, including chemical intermediates, dyes, plastics, and pharmaceuticals. The reaction involves introducing a nitro group (─NO2) onto an aromatic ring through an electrophilic aromatic substitution mechanism....

Ipso Nitration

Ipso nitration involves the substitution of a hydrogen atom with a nitro (-NO2) groups on the carbon adjacent to the aromatic ring. This reaction is typically carried out using a mixture of acids, which produces the nitronium ion (NO2+), the active species in the reaction. The reaction can also be carried out using other nitrating agents....

Electrophilic Substitution Mechanism

The mechanism of the reaction can be broken down into the following steps:...

Nitrating Agents

Some Nitrating Agents that can be used for Nitration are:...

Examples of Nitration

Various example of Nitration with reactions are,...

Factors Affecting Nitration

Here are some factors affecting nitration in pointer format:...

Applications of Nitration

The different applications of Nitration are as follows:...

Environmental Impact of Nitration

Nitration’s environmental impact can be positive and negative, depending on the specific conditions and factors involved. Here are some key points highlighting the environmental impact of nitration:...

Frequently Asked Questions on Nitration

What is Nitration with Example?...